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Can NMN and Ashwagandha Boost Your Stress Resilience?

Stress is the much-dreaded word that you hear in our modern world, where work schedules and personal responsibilities make it sound like it’s an inevitable part of our lives. But what is really stress? Stress is the body's response to any demand or threat, whether physical or psychological. When faced with a stressor, the body undergoes a series of physiological changes, including the release of stress hormones like cortisol and adrenaline. While these changes can be beneficial in the short term, chronic stress can lead to a lot of health problems, including anxiety, depression, cardiovascular disease, and weakened immune function.

Even though our brains are -as always - just trying to help us, dealing with stress and building stress resilience is important for our overall well being. Fortunately, nature offers some powerful allies, such as NMN (Nicotinamide Mononucleotide) and Ashwagandha. These natural supplements can make a real difference in enhancing our resilience to both physical and mental stressors. Let’s explore how NMN and Ashwagandha work to support your body's stress response and bolster overall well-being.


Understanding Resilience


Resilience is an interesting concept that encompasses the ability to bounce back from stress and maintain equilibrium. It's about how effectively we can recover from adversity and continue to function at our best. Enhancing stress resilience involves not only managing stress but also fortifying the body's systems to better handle future stressors. Resilience involves a multifaceted approach to well-being, including physical health, mental health, emotional regulation, adaptability, and preventative measures. 

That’s why resilience means maintaining a healthy body with exercise, diet, sleep, and hydration boosts stress recovery, but also incorporating mindfulness, meditation, and positive thinking, alongside strong social connections into your routine. Emotional regulation, including recognizing stress triggers and self-compassion, is also important. All of these aspects can be enhanced by supplements like NMN and Ashwagandha, which boost the body's stress resilience.


The Role of NMN in Stress Resilience


NMN, or Nicotinamide Mononucleotide, is a molecule that plays a key role in the production of NAD+ (Nicotinamide Adenine Dinucleotide), a vital coenzyme found in every cell of the body. NAD+ is essential for various cellular processes, including energy production, DNA repair, and cellular communication.


Energy Production

One of the primary ways NMN, a NAD+ precursor supplement, supports resilience is through its role in energy production. Stress can deplete the body's energy reserves, leading to fatigue and decreased performance. By boosting NAD+ levels, NMN enhances the efficiency of the mitochondria—the powerhouses of the cell—, which increases energy production. This helps the body meet the heightened energy demands during stressful periods, reducing feelings of fatigue and improving overall endurance.


Cellular Repair and Longevity


Stress causes cellular damage, leading to ageing and disease. NMN, through its role in NAD+ production, supports cellular repair mechanisms. NAD+ activates enzymes called sirtuins, which are particularly important in DNA repair and cellular longevity. By improving these repair processes, this NAD+ booster helps mitigate the damage caused by stress, promoting healthier ageing and reducing the risk of stress-related diseases.


Cognitive Function


Mental resilience is equally important as physical resilience. NMN, the NAD+ booster, has been shown to support cognitive function by improving neuronal energy metabolism and reducing neuroinflammation. By maintaining healthy brain function, NMN helps protect against cognitive decline and supports mental clarity and focus, even under stress.


The Benefits of Ashwagandha


Ashwagandha (Withania somnifera) is an adaptogenic herb that has been used for centuries in traditional Ayurvedic medicine. Adaptogens are natural substances that help the body adapt to stress and maintain homeostasis. Natural Ashwagandha is particularly renowned for its ability to modulate the body's stress response.


Cortisol Regulation


One of the most well-documented benefits of Ashwagandha is its ability to lower cortisol levels. Cortisol, often referred to as the "stress hormone," is released in response to stress and plays a key role in the body's fight-or-flight response. Chronic elevation of cortisol can lead to various health issues, including weight gain, high blood pressure, and impaired immune function. Natural Ashwagandha helps regulate cortisol production, reducing the harmful effects of chronic stress.


Immune Support


Stress can weaken the immune system, making the body more susceptible to infections and illnesses. Natural Ashwagandha has immunomodulatory properties, meaning it can boost the body's immune response while also reducing inflammation. By supporting a balanced immune system, Ashwagandha helps the body fight illness and recover more quickly from stress-induced health issues.


Anxiety and Mood Support


As we mentioned earlier, mental and emotional resilience are also critical factors in our well-being. Ashwagandha has been shown to have anxiolytic (anxiety-reducing) effects, helping to calm the mind and improve mood. It enhances the production of GABA (gamma-aminobutyric acid), a neurotransmitter that promotes relaxation and reduces anxiety. Thanks to its ability to support a calm and balanced mind, natural Ashwagandha helps individuals better cope with stress and maintain emotional stability.


NMN and Ashwagandha Combined 


While NMN and Ashwagandha are great for supporting our well-being on their own, here's a list of reasons why you should consider taking them together. We already talked here about supplement synergy, the best way to maximise their combined benefits and enhance your body's stress resilience more effectively.


Enhanced Energy and Focus


By boosting cellular energy production through NMN and reducing cortisol levels with the best Ashwagandha, people can experience improved physical and mental energy. This combination promotes increased productivity, endurance, and focus, which improve performance under pressure.


Comprehensive Stress Mitigation


NMN supports cellular repair and longevity, while natural Ashwagandha regulates cortisol and promotes relaxation. Together, they address both the physical and mental aspects of stress, providing a holistic approach to resilience. This synergy ensures that the body is better equipped to handle stressors, recover from them, and maintain optimal function.


Immune and Cognitive Health


The combined effects of the best Ashwagandha and the neuroprotective benefits of NMN create a powerful duo for supporting overall health. With this combo, rest assured that you’ll have a strong immune system and healthy cognitive function, and be able to build long-term resilience.



There’s nothing like NMN and Ashwagandha to build stress resilience and better tolerate stress and the stress hormones released by our body in difficult times. Simply Nootropics’ line includes both NMN Powder and Ashwagandha as a main ingredient in Simply Nootropics Essentials. By giving your body the very best, you can also give yourself the chance to perform better and support your physical and emotional well-being. Try Simply Nootropics and see the difference NMN and Ashwagandha can make in your life.

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