What Is Nicotinamide Riboside (NR)?

Nicotinamide Riboside (NR) is a form of vitamin B3 (niacin) that acts as a precursor to NAD+ (Nicotinamide Adenine Dinucleotide), a molecule essential for cellular energy production and repair. NAD+ plays a critical role in numerous biological processes, including DNA repair, energy metabolism, and cellular regeneration.
As the body ages, NAD+ levels naturally decline, leading to reduced cellular efficiency, slower tissue repair, and visible signs of ageing. By boosting NAD+ levels, NR helps counteract these effects, promoting overall cellular health and vitality.

How Does NR Support Collagen Production?

NR enhances collagen production indirectly by boosting NAD+ levels, which are essential for the cells responsible for collagen synthesis. Fibroblasts, the cells that produce collagen, rely on NAD+ for energy and efficient function. By replenishing NAD+ levels, NR ensures these cells can produce and maintain collagen effectively.
Additionally, NAD+ activates sirtuins, a family of proteins involved in cellular repair and longevity. Sirtuins play a key role in reducing oxidative stress and inflammation, both of which can degrade collagen over time. By minimising these harmful effects, NR creates an environment where collagen can thrive, improving skin elasticity and joint health.

What Are the Benefits of Combining NR and Collagen?

When used together, Nicotinamide Riboside (NR) and collagen offer a synergistic approach to maintaining youthful skin, flexible joints, and overall tissue resilience. Collagen provides the structural foundation for skin, cartilage, and connective tissue, while NR ensures that the cells responsible for collagen synthesis are adequately energised and protected from stressors.
This combination supports skin elasticity and hydration, reducing wrinkles and maintaining a smooth, youthful appearance. In joints, collagen strengthens cartilage, while NR helps reduce inflammation, improving mobility and reducing discomfort. Furthermore, NR's ability to combat oxidative stress prevents the degradation of collagen caused by free radicals, enhancing its long-term effectiveness. Together, NR and collagen amplify each other's benefits, ensuring comprehensive support for connective tissue health.

Who Should Consider NR for Collagen Support?

NR is particularly beneficial for individuals experiencing collagen-related issues due to ageing or high levels of physical activity. Ageing adults can benefit from NR’s ability to replenish NAD+ levels, which naturally decline over time, slowing collagen synthesis and contributing to wrinkles, joint stiffness, and weakened connective tissues. By restoring cellular energy, NR supports the efficient production of collagen, helping to combat these age-related effects.
Active individuals and athletes can also find value in NR, as it reduces oxidative stress and inflammation caused by physical exertion. This not only protects collagen but also promotes faster recovery and sustained joint health. For those focused on maintaining or enhancing their skin, NR complements collagen supplements by energising the fibroblasts that drive skin repair, improving hydration, and reducing visible signs of ageing.

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