WHAT IS NAD+?

Nicotinamide Adenine Dinucleotide (NAD+), the powerful molecule with a big name

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We often care for our health at a superficial level, focusing on our hair, teeth, and skin. But taking care of your health from the inside is just as important. 

At a cellular level, trillions of processes are happening every second to keep your body and mind going. Among others, you can thank NAD+ for this. 

This molecule is involved in over 500 of these processes, making it a key player in the game of cellular health.

Key Processes Powered by NAD+

We’ve summed up some of the most important processes for you.

NAD+ Components

It’s a lot, we know, but NAD+ handles it all. So, what exactly is this powerful molecule?

Let’s start with the presentations. NAD+ stand for:

Dinucleotide

A key component of NAD+, derived from vitamin B3 (niacin), one of the essential vitamins crucial for your body's health.

Adenine

The other vital component of NAD+, a base that is an integral part of both DNA and RNA.

Dinucleotide

This term describes the structure of NAD+, consisting of two linked molecules: Nicotinamide and Adenine.

NAD+ is far from a one-time-use molecule. It continuously cycles between its two forms, NAD+ and NADH, shuttling electrons throughout your body. This constant recycling is essential for maintaining the balance of cellular energy. Through this process, NAD+ helps convert nutrients into ATP, the energy currency that powers nearly every function in your cells.

On NAD+'s official passport, you'd read that it’s a coenzyme, meaning it partners with enzymes, those essential proteins that accelerate chemical reactions in your body. Enzymes rely on NAD+ to carry out many tasks, especially in energy production, maintaining cell function, and supporting healthy ageing.

NAD+ Health Benefits

1 Molecule, Endless Health Benefits

Energy Production

Do you remember what we said earlier about ATP? Yes, that’s right: NAD+ converts the food you eat into ATP (adenosine triphosphate), the primary energy currency of your cells.

DNA Repair

Every day, your DNA is exposed to damage from environmental factors like UV rays, toxins, and even normal metabolic processes. NAD+ helps repair DNA damage by activating PARPs, enzymes that fix broken DNA strands. This supports the integrity of your genetic material and prevents mutations linked to diseases.

Healthy Ageing

NAD+ supports healthy ageing by maintaining cellular function, reducing oxidative stress, and improving DNA repair mechanisms. With enough NAD+, your cells are better equipped to handle the challenges of ageing, leading to a longer, healthier life.

Metabolic Support

NAD+ is also deeply involved in your metabolism, which is the set of chemical reactions in your body that convert food into energy. NAD+ interacts with metabolic regulators to help you maintain a healthy weight and ensures your body has the energy it needs throughout the day.

Cognitive Function

Your brain is one of the most energy-demanding organs in your body, and it relies on NAD+ to meet its energy needs. NAD+ not only fuels the brain’s energy production but also supports cognitive function. Maintaining healthy NAD+ levels can help protect against neurodegenerative diseases and improve memory.

Immune Function

NAD+ is also involved in the production of molecules that regulate inflammation and help your body fight off infections. Healthy NAD+ levels mean that your immune system functions optimally, making you better at recovering quickly from illnesses.

Cardiovascular Health

Exciting news: NMN may also help slow down neurodegenerative diseases like Alzheimer’s and Parkinson’s by protecting neurons, reducing brain inflammation, and supporting DNA repair.

Skin Health

NAD+ impacts your appearance by supporting DNA repair and cellular regeneration, which contributes to maintaining healthy, youthful skin. It assists in repairing damage caused by UV exposure and environmental stressors, diminishing  the appearance of fine lines, wrinkles, and other signs of ageing.

NAD+ Decline and Its Impact

Thankfully, NAD+ is naturally produced by our bodies and can be further boosted through a healthy diet rich in vitamin B3 and tryptophan, and regular exercise, which enhances energy production and overall vitality.

But let’s do some math: the average adult has around 37 trillion cells, and each one of them relies on NAD+ to function properly. That’s a staggering demand on your body’s NAD+ supply… one that diet and exercise alone can’t fully meet.

And that’s not all:

NAD+ levels naturally start to decline as early as your mid-20s, partly due to DNA damage.

By the age of 40, your NAD+ levels can drop by as much as 50%.

And by the time you reach 60, those levels could be down by as much as 75%.

What happens is that NAD+ gets a bit "tired" of constantly recycling itself and carrying out its duties, like repairing DNA and producing energy. With more stress and damage to handle, it struggles to keep up, leading to lower levels over time.

But what does this dramatic decline in NAD+ levels mean for you? It impacts almost every aspect of your health, including:

Getting those NAD+ levels up again is not that complicated. At Simply Nootropics, we’ve made it simple, effective, and game-changing.

Your energy levels

As NAD+ decreases, so does your cellular energy production, leaving you feeling fatigued and less able to keep up with daily demands.

Your DNA repair

With less NAD+ available, your body becomes less efficient at repairing DNA damage, increasing the risk of genetic mutations and age-related diseases.

Your cognitive function

Lower NAD+ levels mean reduced support for brain health, which can lead to memory issues, slower thinking, and a higher risk of neurodegenerative diseases.

Your metabolism

A drop in NAD+ can slow down your metabolism, making it harder to maintain a healthy weight and contributing to metabolic disorders like diabetes.

Your muscle strength

As NAD+ levels fall, so does your muscle function, which can lead to weakness, reduced mobility, and a higher risk of falls and injuries.

Your immune system:

NAD+ helps regulate immune function, and lower levels can weaken your body's ability to fight off infections and inflammation, making you more vulnerable to illnesses.

Your skin health:

NAD+ is essential for skin repair and regeneration. As levels decline, you may notice more signs of ageing, such as wrinkles, fine lines, and reduced elasticity.

Boost your NAD+ level today

NAD+ Boosters

But it doesn’t have to be like that. Thank science for NAD+ boosters, the only solution to effectively increase NAD+ levels in your body.

NAD+ boosters are supplements specifically designed to elevate NAD+ levels, helping you reclaim the energy, vitality, and health you deserve.

These supplements can boost NAD+ levels by 40-60%, effectively restoring them to levels similar to those of a much younger you. It’s literally like turning back the clock on your cellular health.

Meet the best NAD+ boosters

NR

Nicotinamide Riboside (NR) is a powerful form of vitamin B3 and a precursor to NAD+. Once ingested, NR is rapidly absorbed and converted into NAD+.

Research has shown that daily supplementation with this NAD+ booster can increase NAD+ levels by as much as 60%, enhancing cellular health, energy production, and cognitive function.

NMN

NMN is a highly effective precursor to NAD+, directly contributing to its production in your cells. 

Within as few as 4-8 weeks of consistent use, NMN has been shown to provide short-term benefits, such as enhanced physical performance and increased energy levels. Long-term benefits include healthy ageing by improving metabolic function and preserving muscle vitality.

Taking the Next Step

So, if you’re ready to stop the ticking and put those clock hands back, learn more about the best NAD+ boosters.

Increase your NAD+ levels with our best sellers:

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FAQs

What does NAD+ do?

Nicotinamide Adenine Dinucleotide (NAD+) is a vital coenzyme found in all body cells. It plays a crucial role in energy metabolism by converting nutrients into energy and supports numerous biological processes such as DNA repair, cellular signalling, and maintaining overall cellular health. Additionally, NAD+ is essential for the function of sirtuins, enzymes linked to longevity and metabolic regulation, making it a key factor in promoting healthy ageing and cellular function.

Does NAD+ actually work?

Yes, NAD+ supports vital cellular functions, especially those involved in energy production and repair. According to research, increasing NAD+ levels can improve energy levels and cognitive function, and possibly even slow down the ageing process, among other health benefits. 

Is NAD+ the same as vitamin B3?

NAD+ is not the same as vitamin B3, but they are closely related. NAD+ is derived from vitamin B3 (niacin) and other precursors like nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN). While vitamin B3 contributes to the production of NAD+, taking a NAD+ booster directly can be a more effective way to increase NAD+ levels in the body.

What does NAD+ therapy do?

NAD+ therapy involves the injection of NAD+ directly into the bloodstream, usually via an intravenous (IV) infusion. This therapy aims to quickly increase NAD+ levels in the body to improve energy metabolism, cognitive function, and overall cellular health. NAD+ therapy is often used for its potential anti-aging benefits, including enhanced mental clarity and support for recovery from addiction.

 Can NAD reverse ageing?

Increasing NAD+ levels can help slow down certain parts of the ageing process by improving cellular repair, increasing energy production, reducing inflammation, and supporting healthy brain function. NAD+ is strongly linked to numerous mechanisms that resist ageing, and these advantages are backed by a significant amount of research.

Who should take NAD+?

NAD+ supplements can help those who want to enhance their general energy levels, support healthy ageing, or improve cognitive performance. Individuals aged 30 and above, particularly professionals in high-stress jobs, those experiencing chronic fatigue, or those facing age-related health deterioration, may find NAD+ supplements especially beneficial.

How long can I take NAD+?

NAD+ supplements are thought to be safe for long-term usage, so they can usually be used for a longer period of time. However, the right length of time and dosage should be chosen based on each person's unique needs and health objectives, ideally with the assistance of a medical professional.

At what age does NAD+ start to decline?

NAD+ levels naturally start to decline as early as your mid-20s, partly due to DNA damage. By the age of 40, your NAD+ levels can drop by as much as 50%, and by the time you reach 60, those levels could be down by as much as 75%. This decline is associated with reduced cellular energy production and an increase in age-related health issues.

What are the symptoms of NAD deficiency?

Symptoms of NAD+ deficiency can include fatigue, muscle weakness, cognitive decline, and a general decrease in physical and mental stamina. Other signs might include slower recovery from exercise, reduced ability to manage stress, and an overall sense of feeling "run down."

How do I check my NAD+ level?

Currently, checking NAD+ levels directly is not as straightforward as a standard blood test. However, some specialised laboratories offer tests that can measure NAD+ and its related metabolites in the blood. As a general rule, NAD+ levels should start decreasing by about 50% by the age of 40, continuing to decline as you age.

What is the best NAD+ supplement?

The best NAD+ supplement depends on individual needs and health goals. Popular forms include Nicotinamide Riboside (NR) and Nicotinamide Mononucleotide (NMN), both of which effectively boost NAD+ levels. For a reliable option, check out Simply Nootropics for the best NAD+ boosters, which are made in New Zealand with imported ingredients, third-party tested, and free of nasties.

What are the side effects of NAD+ supplements or therapy?

NAD+ supplements are generally considered safe with few reported side effects. Some mild symptoms can include nausea, headaches, or digestive discomfort. NAD+ therapy may have more noticeable side effects, such as flushing, exhaustion, or muscle soreness, especially at high doses.